The EPIC standard for industrial SBCs is widely used with a lot of CPU options and offers rich IO options, including compatibility with PC/104 expansion modules.
Ultra-reliable Embedded Single Board Computers (SBC) from Impulse with long-lifetime supply and revision control. Available in 2.5" Pico-ITX, 3.5" Biscuit, PC/104 and EPIC form factors, suitable for a wide range of embedded OEM applications.